literature

HBV mutation literature information.

Mutations in the HBV PreS/S gene related to hepatocellular carcinoma in Vietnamese chronic HBV-infected patients.

PMID: 35390033 2022 PloS one

Table: L95W

Nearly half of Ultrio plus NAT non-discriminated reactive blood donors were identified as occult HBV infection in South China.

PMID: 31269905 2019 BMC infectious diseases

Discussion: Consistently, a Chinese study reported that a mutation L95 W could impair virion secretion and change antigenicity.

Discussion: Moreover, mutations outside MHR including T47K (13%) and L95 W (4.3%) were also observed in our population.

Effects of amino acid substitutions in hepatitis B virus surface protein on virion secretion, antigenicity, HBsAg and viral DNA.

PMID: 27650283 2017 Journal of hepatology

Result: we conclude that mutants sE2G, sL95W and sL98V might negatively influence HBV virion secretion and mutants sC69* and sG145R may influence HBV replication.

Discussion: We identified several new HBV mutations (sE2G, sL21S, sR24K, sC69*, sL95W and s

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