rt269I Type of Hepatitis B Virus (HBV) Polymerase versus rt269L Is More Prone to Mutations within HBV Genome in Chronic Patients Infected with Genotype C2: Evidence from Analysis of Full HBV Genotype C2 Genome.
Abstract: We also found that there are a total of 19 signature single nucleotide polymorphisms (SNPs), of which 2 and 17 nonsynonymous mutation types were s
Result: The L213I/S in the S region, which tended to be higher in rt269I HBV strains than in rt269L (q = 0.054), has been reported to be related to disease progression in chronic patients).
Result: We found a total of five types of signature NS mutations in the S ORF (I84T/M/L/V and A90T/V in PreS1, F141L in PreS2, and I68T and L213I/S in S).
Quasispecies variant of pre-S/S gene in HBV-related hepatocellular carcinoma with HBs antigen positive and occult infection.
Result: Differences in the major populations were attributed to the I126S/T, Y200F/S, and Y206C/H/S mutations, while those in the minor populations were attributed to the L21F/S, L42F/S, W182Stop, and L213F/I/T mutations.
Table: L213F/I
Molecular evolution of hepatitis B vaccine escape variants in China, during 2000-2016.
Abstract: Four sites (A5T/S, L21S, T/A126S and T/N131I/A) and 13 sites (N3S, T5A, G10Q/R/E, L21S, T47K/A/V, L98V/P, I/S126N/V/T, Q129H/R/L, T131P/I/N/A, G145A/R, L175S/F, L213I/S, V224A/G) were found to be under positive selection in genotype B and C HBV vaccine escape strains, re
Mutation profiling of the hepatitis B virus strains circulating in North Indian population.
Novel point and combo-mutations in the genome of hepatitis B virus-genotype D: characterization and impact on liver disease progression to hepatocellular carcinoma.
Result: Additionally, a single point mutation L213I in C-terminal region of surface was encountered at a high frequency in LC (45%) and HCC (50%) patients but was statistically insignificant (p = 0.085).
Result: Patients harbouring T1753C in BCP, T147C in CTL epitope of core and L213I mutation in surface were found more in HBeAg positive Result: and A1762T/G1764A with L213I in surface region [67% (6/9) vs.
Subgenotypes and mutations in the s and polymerase genes of hepatitis B virus carriers in the West Bank, palestine.
Discussion: Table 1 shows that the mutations found upstream-I86F, I92T, and I110L-and those found downstream-T189I, Y200F, S204R, Y206L, S207N, S210R, L213I, and L213F-were recorded in different studies but were not associated with critical functions (Table 1).
Hepatitis B viral surface mutations in patients with adefovir resistant chronic hepatitis B with A181T/V polymerase mutations.
PMID: 20119580
2010
Journal of Korean medical science
Result: Other mutations that we detected in the S gene include S3N (Group P=4, Group C=2), I68T (Group P=3, Group C=1), I126T (Group P=4, Group C=1), and L213I (Group P=6, Group C=1).
HBV mutation literature information.
PMID: 
2022
PloS one
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