HBV mutation literature information.


  Molecular characterization of hepatitis B virus (HBV) isolated from a pediatric case of acute lymphoid leukemia, with a delayed response to antiviral treatment: a case report.
 PMID: 35361141       2022       BMC pediatrics
Table: L100I
Discussion: The cL100I mutation is found within the overlapping CD4+ T- and CD8+ T-cell epitope of core gene.


  Precore/core mutations of hepatitis B virus genotype D arising in different states of infection.
 PMID: 35415256       2022       Clinical and experimental hepatology
Introduction: In a study conducted in the Korean population, the five HBcAg mutations P5H/L/T, E83D, I97F/L, L100I, and Q182K/Stop were significantly more frequent in subjects with chronic hepatitis and cirrhosis.


  The Correlation Between Hepatitis B Virus Precore/Core Mutations and the Progression of Severe Liver Disease.
 PMID: 30406036       2018       Frontiers in cellular and infection microbiology
Introduction: Furthermore, five HBcAg mutations identified in a Korean population, P5H/L/T, E83D, I97F/L, L100I, and Q182K/Stop, were shown to be significantly enriched in HCC patients compared with patients at earlier disease stages, including those with cirrhosis and chronic hepatitis (Kim et al.,).


  Molecular characterization of HBV strains circulating among the treatment-naive HIV/HBV co-infected patients of eastern India.
 PMID: 24587360       2014       PloS one
Discussion: A recent study showed that HBV/C related P5H, I97F/L and L100I mutations were significantly associated with HCC.


  Naturally occurring precore/core region mutations of hepatitis B virus genotype C related to hepatocellular carcinoma.
 PMID: 23071796       2012       PloS one
Abstract: Six (preC-W28*, C-P5H/L/T, C-E83D, C-I97F/L, C-L100I and C-Q182K/*) and seven types (preC-W28*, preC-G29D, C-D32N/H, C-E43K, C-P50A/H/Y, C-



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