HBV mutation literature information.


  PreS1 Mutations Alter the Large HBsAg Antigenicity of a Hepatitis B Virus Strain Isolated in Bangladesh.
 PMID: 31952213       2020       International journal of molecular sciences
Conclusion: preS1 C2964A, RT domain I91L, and small HBsAg N3S mutations were found, all of which have clinical
Result: However, some mutations (H9Y, N13H, I91L, I269L, and V278I) were found in the RT domain that are not associated with drug resistance, according to Geno2pheno:hbv.
Result: Only one putative NA-resistant mutation, I91L, was found, and no primary, secondary, pre-treatment, or drug-resistant mutations were observed in the RT domain of Pol.


  Naturally occurring hepatitis B virus reverse transcriptase mutations related to potential antiviral drug resistance and liver disease progression.
 PMID: 29713126       2018       World journal of gastroenterology
Method: Our literature based pooled incidence data showed that several putative or pretreatment mutations, including rtI91L, mutations in 6 positions of A-B interdomain (rtY124H, rtY126C/R/H, rtT128I/N, rtD134E/N, rtN139D/E/H/K/Q and rtW153Q/R/E), rtF221Y and rtI224V, were encountered with high frequency from t


  Mutational analysis of reverse transcriptase and surface proteins of patients with partial virological response during mono and combination antiviral therapies in genotype D chronic hepatitis B.
 PMID: 27504160       2016       Electronic physician
Abstract: T54N, L80I/V, I91L/V, L180M, M204I/V, Q215P/S, and F221Y/S showed the highest number of mutations in all groups with different frequencies.


  Characterization of antiviral resistance mutations among the Eastern Indian Hepatitis B virus infected population.
 PMID: 23409946       2013       Virology journal
Introduction: Recently, HBVrt domain mutations which have been reported in the literature as supposed drug resistant mutations but are not verified experimentally were classified as putative NA resistant (NAr) mutations (such as S53N, T54N, L82M, V84M, S85A, I91L, Y126C, T128I, T128N, N139D, W153Q, F166L).
Result: All the isolates having rt
Table: I91L


  Drug-related mutational patterns in hepatitis B virus (HBV) reverse transcriptase proteins from Iranian treatment-naive chronic HBV patients.
 PMID: 23596461       2013       Hepatitis monthly
Table: I91L


  Characterization of the occult hepatitis B virus variants circulating among the blood donors from eastern India.
 PMID: 24302857       2013       TheScientificWorldJournal
Abstract: Considerable prevalence of differential BCP (1752C, 1753C, 1762T/1764A, 1753C+1762T/1764A, 1773C, and 1814C) and reverse transcriptase (rt) gene (rtI91L, rtL93P, rtS106C, rtR110G, rtN118T, rtS119T, rtY126H, rtG127W/R, rtC136R, and



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