literature

HBV mutation literature information.

HBV genotypes and drug resistance mutations in antiretroviral treatment-naive and treatment-experienced HBV-HIV-coinfected patients.

PMID: 27167598 2017 Antiviral therapy

Method: The sequences were examined for known vaccine escape mutations (sG145R/A, sP142S, sI/T126A/N/I/S, sQ129H/R, sM133L, sD144A/E, sP120S/E, sK141E<

Result: All patients had the N204S mutation, and all but patient 132E had the sI126T mutation.

Mutations in the S gene and in the overlapping reverse transcriptase region in chronic hepatitis B Chinese patients with coexistence of HBsAg and anti-HBs.

PMID: 26613893 2016 The Brazilian journal of infectious diseases

1Abstract: Mutation sI126S/T within the ""a"" determinant was the most frequent change, and only patients from group I had the sQ129R, sG130N, sF134I, sG145R amino acid changes, which are known to alter immunogenicity."

Hepatitis B surface antigen variants in voluntary blood donors in Nanjing, China.

PMID: 22500577 2012 Virology journal

Result: D99N, Y100F, Q101R/H, L110I, T113S, S114T, S117T, T118M, I126T/V, W165L, and V168A, which may be associated with antigenicity of HBsAg.

Molecular and clinical characteristics of hepatitis B virus in Korea.

PMID: 20513074 2010 Journal of medical virology

Abstract: A number of amino acid/nucleotide substitutions were associated with HCC, namely sR24K (HBsAg), SI126T (HBsAg), and pcA1846T (precore gene) mutations (P = 0.029, 0.001, and 0.008, respectively).

Hepatitis B viral surface mutations in patients with adefovir resistant chronic hepatitis B with A181T/V polymerase mutations.

PMID: 20119580 2010 Journal of Korean medical science

Result: Other mutations that we detected in the S gene include S3N (Group P=4, Group C=2), I68T (Group P=3, Group C=1), I126T (Group P=4, Group C=1), and L213I (Group P=6, Group C=1).

Discussion: In our study, an I126T mutation was detected in 4 of 13 ADV mutants and one of nine control cases.

Discussion: To determine the clinical significance of I126T, T131P, and T140S mutations, further studies are required.

[Analysis on mutation of S gene and P gene of hepatitis B virus in two counties of Sichuan Province].

PMID: 20077675 2009 Zhongguo yi miao he mian yi

Abstract: RESULTS: Of 47 serum samples from patients with chronic HBV infection, amino acid mutation in 'a' determinant occurred in 12 samples (25.53%,12/47), correlating with T126A, I126T/S, P127T, T131N, M133L, M133T and T140I; high proportion of mutation clustered in first loop of 'a' determinant (92.86%,13/14), rtV207I mutation in C domain of reverse transcription occured in one sample.

A serological and molecular survey of hepatitis B in children 15 years after inception of the national hepatitis B vaccination program in eastern China.

PMID: 19626618 2009 Journal of medical virology

Abstract: Mutations of I126T, amino acid 137 (nt553T deletion mutation), G145A, G145R, and F158S were found in the children; the mutations of amino acid 137 and F158S have not been reported previously.

"Molecular analysis of hepatitis B virus ""a"" determinant in asymptomatic and symptomatic Mexican carriers."

PMID: 17217533 2007 Virology journal

Result: T113S, S114T, R122K, I126T and P127L were the most frequent in both asymptomatic and symptomatic patients; whereas A159G, R160K, F161Y and V168A were more frequent in symptomatic patients.

Table: I126T

Browser Board

Co-occurred Entities

Filtrator