literature

HBV mutation literature information.

Prevalence, genotype distribution and mutations of hepatitis B virus and the associated risk factors among pregnant women residing in the northern shores of Persian Gulf, Iran.

PMID: 35271684 2022 PloS one

Result: Seven amino acid substitutions were detected in HBsAg of strains isolated from pregnant women, including the conversion of Ile Leu at amino acid 110 (I110L), Thr Pro at amino acid 127 (T127P), Asp Glu at amino acid 144 (D144E), Ser Ala at amino acid 154 (S154A), Gly Ala at amino acid 159 (G159A), Ala Gly at amino acid 166 (A166G) and Ala Val at amino acid 168 (A168V) of

Table: I110L

Mutations in the HBV PreS/S gene related to hepatocellular carcinoma in Vietnamese chronic HBV-infected patients.

PMID: 35390033 2022 PloS one

Table: I110L/Q

Detection of circulating hepatitis B virus immune escape and polymerase mutants among HBV-positive patients attending Institut Pasteur de Bangui, Central African Republic.

PMID: 31682960 2020 International journal of infectious diseases

Discussion: In addition to the three IEMs identified, several surface protein mutations were identified (sP56Q, sT57I, sN59S, sP62L, sI110L, sS140T, sE164G, sS207N, and sL216*), which have also been reported in previous studies (Mello et al.,; Lin et al.,; Munshi et al.,; Qin and Liao,).

Molecular and serological characterization of occult hepatitis B virus infection among patients with hemophilia.

PMID: 30908666 2019 Journal of medical virology

Abstract: sR73H, sI110L, sP120A, sP127T, sQ129H, sG130R, and sC137S were shown to be the most determinant escape mutation and OBI-relevant mutants.

[HBV pol/S gene mutations in chronic hepatitis B patients receiving nucleoside/nucleotide analogues treatment].

PMID: 31130119 2019 Mikrobiyoloji bulteni

Abstract: Because of the HBV pol/S gene overlapping, in 27 patients immun-selected amino acid substitutions (sI110L, sT127P, sS114A, sT123A), in nine patients HBIg selected escape mutants (sP120R, sT123N, sE164D, sY134F, sQ129H, sT118A,

Deep sequencing of hepatitis B surface antigen gene in the preserved umbilical cords in immunoprophylaxis failure against mother-to-child HBV transmission.

PMID: 31752732 2019 BMC infectious diseases

Conclusion: Of the 10 minor variants, four (I110L, S113 T, K122Q, and T143S) were detectable in all of the umbilical cord samples and all serum samples.

Table: I110L

Evaluation of the pol/S Gene Overlapping Mutations in Chronic Hepatitis B Patients in Northern Cyprus.

PMID: 31880877 2019 Polish journal of microbiology

Result: The mutation patterns were sI110L + sS193L, sP120L + + sT123N + sT126I + sA128V + sY134H + sD144E + +sG145A, sT118A+sP127T, s Table: I110L

A systematic review of hepatitis B virus (HBV) drug and vaccine escape mutations in Africa: A call for urgent action.

PMID: 30080852 2018 PLoS neglected tropical diseases

Result: sI110L occurring in genotype A (3/69, 4.3%), D (4/69, 5.8%) and E (11/69, 15.9%) associated with immunoglobulin resistance.

Table: I110L

HBV genotypes and drug resistance mutations in antiretroviral treatment-naive and treatment-experienced HBV-HIV-coinfected patients.

PMID: 27167598 2017 Antiviral therapy

Method: The sequences were examined for known vaccine escape mutations (sG145R/A, sP142S, sI/T126A/N/I/S, sQ129H/R, sM133L, sD144A/E, sP120S/E, sK141E, sP134I, and sT116N), immunoprophylaxis escape mutations (

Hepatitis B virus sequencing and liver fibrosis evaluation in HIV/HBV co-infected Nigerians.

PMID: 28376292 2017 Tropical medicine & international health

Result: Outside of the 'a' determinant, common mutations occurred at residues 164 (sE164G in 5/46 and sE164A in 1/46), 110 (sI110L in 5/46) and 184 (sA184V in 2/46).

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