literature

Hepatitis B virus mutations, expression quantitative trait loci for PTPN12, and their interactions in hepatocellular carcinoma.

PMID: 27075395 2016 Cancer medicine

Result: As shown in Figure 1, rs11489585 multiplicatively interacted with G1799C.

Result: Of those 19 hotspot mutations, C1653T, T1674C/G, A1703G, G1719T, T1727A/G, T1753C, A1762T, G1764A, G1799C, G1899A, G1915A/C, and C1969T were significantly associated with an increased risk of HCC, whereas C1673T, A1726C, C1730G, and

PMID: 26568165 2015 Scientific reports

Result: Of those 19 hotspot mutations, C1653T, T1674C/G, A1703G, G1719T, T1727A/G, T1753C, A1762T, G1764A, G1799C, G1899A, G1915A/C and C1969T were significantly associated with an increased risk of HCC, whereas C1673T, A1726C, C1730G and A1752G were significantly associated with a reduced risk of

PMID: 23903686 2013 Brazilian journal of medical and biological research

Abstract: Seven mutation patterns (C1653T, G1719T, G1730C, T1753C, A1762T, G1764A, and G1799C) were associated with C2, and four patterns (C1810T, A1846T, G1862T, and G1896A) were associated with B2.

Discussion: Univariate analyses showed that 6 mutation patterns (C1653T, G1730C, T1753C, A1762T, G1764A, and G1799C) located in the CP

HLA-DP polymorphisms affect the outcomes of chronic hepatitis B virus infections, possibly through interacting with viral mutations.

PMID: 24006435 2013 Journal of virology

Abstract: HLA-DP polymorphisms promoting HBV clearance were associated with a lower prevalence of mutations increasing HCC risk (C1653T, T1674C/G, A1846T, G1896A and pre-S2 mutations and pre-S deletion in genotype C) and a higher prevalence of mutations decreasing HCC risk (G1652A, T1673C, T1674C, G1719T, G1730C, and G1799C in genotype B and A1727T in genotype C).

Associations between hepatitis B virus mutations and the risk of hepatocellular carcinoma: a meta-analysis.

PMID: 19574418 2009 Journal of the National Cancer Institute

Table: G1799C

Longitudinal study on mutation profiles of core promoter and precore regions of the hepatitis B virus genome in children.

PMID: 15240859 2004 Pediatric research

Abstract: Higher frequency of A1775G and G1799C mutation rates and lower frequency of A1752G mutation rate were found in the seroconverters.