Prevalence, genotype distribution and mutations of hepatitis B virus and the associated risk factors among pregnant women residing in the northern shores of Persian Gulf, Iran.
Result: T1753A, A1761C, G1764T/A, C1766G/T, and C1773T mutations were detected in the BCP region.
Result: Of these, T1753A and A1761C mutations were detected in one sample (HB55); and G1764T/A, C1766G/T, and C1773T mutations were detected in two samples (HB35 and HB55).
Molecular characterization of hepatitis B virus basal core promoter and precore region of isolates from chronic hepatitis B patients.
PMID: 34111075
2021
JPMA. The Journal of the Pakistan Medical Association
Abstract: A rare G1764T mutation was also detected in 6(12%) isolates.
Hepatitis B virus drug resistance mutations in HIV/HBV co-infected children in Windhoek, Namibia.
Result: Additional substitutions were observed in the upper regulatory region (URR) and BCP regions: patient 2C carried the HBV URR mutant G1728A and BCP mutant G1764T/C1766G, and HBV from patients 6C and 7C carried BCP T1768A and URR C1678T mutants, respectively.
Table: G1764T/C
Discussion: The G1764T/C1766G BCP double mutation is enriched among cirrhotic patients, and combined core mutations are more common in children with
Nucleotide Substitutions in Hepatitis B Viruses Derived from Chronic HBV Patients.
PMID: 31308922
2019
Mediterranean journal of hematology and infectious diseases
Result: However, none of the patients with A1762T/G1764A mutation carried the G1764T/C1766G mutant (Table 2).
Discussion: More extensive research work is needed to explore the tendency to either A1762T/G1764A or Discussion: None of the patients with G1764T/C1766G mutation carried A1762T/G1764A substitution.
Discussion: When there is G1757A, the C1766G/G1764T double mutant is more efficient than the A1762T/G1764A mutation.
Molecular characterization of hepatitis B virus in Vietnam.
Result: T1753C, G1757A, A1762T, G1764A and C1766G mutations were identified in 11.1% (5/135), 7.4% (10/137), 25.9%% (35/135), 24.4% (33.135) and 2.2% (3/135) of the isolates and A1762T and G1764 T mutations were significantly more frequent in the genotype C1 isolates (p < 0.001) (Table 3).
Result: BCP/preC/core gene mutation: BCP mutations at T1753C, G1757A, A1762T
Discussion: A1762T & G1764 T double mutation).
Variability in the precore and core promoter region of the hepatitis B virus genome.
Abstract: A novel association of mutation C1773T with G1764T, C1766A, and G1757A was also found within a site already suggested to be a putative binding site for HNF-3.
Abstract: This novel association is proposed by us to be of importance for additional binding of HNH-2 to this site and is a better indicator of the emergence of the double mutation G1764T and C1766A than the G1757A mutation proposed previously.
Correlation between viral load of HBV in chronic hepatitis B patients and precore and Basal core promoter mutations.
Result: In the present study, we found two patterns of basal core promoter mutations included A1762A/G1764T and A1762T/G1764A.
Association of Hepatitis B Virus Mutations of A1846T and C1913A/G With Acute-on-Chronic Liver Failure Development From Different Underlying Chronic Liver Diseases.
Result: However there were no significant differences in previous reported hotspot mutations (T1753V, A1762T, G1764T, G1896A, and G1899A) between either CHB and ACLF-CHB patients or Discussion: In comparison with CHB patients, the HBV isolates in LC patients had higher frequencies of the mutations in BCP/PC region, which included A1762T/G1764T, T1753V, and/or G1896A.
Molecular characterization of hepatitis B virus in liver disease patients and asymptomatic carriers of the virus in Sudan.
Introduction: The basal core promoter (BCP) gene is a gene frequently changed in HBV as a double mutation (A1762T/G1764T) and has been found to be a codeterminant of HCC development and rapid disease progression in several populations.
HBV mutation literature information.
PMID: 
2022
PloS one
Browser Board
Co-occurred Entities
Filtrator
ViMRT