Abstract: sM133L and sG145R variants were also present in patients with the YMDD mutation.
Molecular Characterization of Pre-Core/Core and S Region of Hepatitis B Virus in Hemodialysis Patients With Occult Hepatitis B Infection.
PMID: 26587212
2015
Jundishapur journal of microbiology
Discussion: determined three different S gene mutations (L109R, C137W, G145R) in a patient with occult hepatitis B, which led to false negative results for HBsAg but positive for HBsAb.
Discussion: reported that out of 239 HBsAg negative patients, nine (3.8%) were HBV-DNA positive and seven of the nine (78%) showed mutations in the S region (G145R).
YMDD Motif Mutation Profile Among Patients Receiving Liver Transplant Due to Hepatitis B Virus Infection With Long Term Lamivudine/Immunoglobulin Therapy.
Result: The obtained results demonstrated three types of escape mutations (Y134N, I110V, G145R) in four subjects with drug resistance mutations and higher viral load (Table 4) as well.
Table: G145R
Short duration of lamivudine for the prevention of hepatitis B virus transmission in pregnancy: lack of potency and selection of resistance mutations.
Result: The classical diagnostic/vaccine escape mutations, G145R and D144E, could not be detected
Discussion: However, in this domain (loop 2) the most prominent vaccine escape mutations sG145R and sD144E/A were not found in the patient collective.
Discussion: Other vaccine escape mutations, especially the G145R and D144E/A mutation, could not been detected.
Discussion: The best-described and stable vaccine escape mutations are the sG145R, sD144E/A, and sP120T mutations.
Spontaneous HBsAg loss in Korean patients: relevance of viral genotypes, S gene mutations, and covalently closed circular DNA copy numbers.
PMID: 25320728
2014
Clinical and molecular hepatology
Discussion: A mixture of D144G/D144A or combined D144E / G145R mutations were detected after hepatitis B immune globulin treatment.
Discussion: In a previous report, a combination of amino acid changes in the surface protein, including G145R, was found to cause secretion defect of HBsAg.
Subgenotypes and mutations in the s and polymerase genes of hepatitis B virus carriers in the West Bank, palestine.
Abstract: Various mutations existed within the S gene; in five patients four known escape mutations including the common G145R and D144E were found.
Discussion: The other four mutations found in the a determinant-T126S, P127S, D144E, and G145R-are known escape mutants and were detected in five Palestinian D1 samples accounting for 12.5% of the total 40 samples.
Discussion: Two of these samples presented with the escape mutations D144E and G145R simultaneously, while the other three samples presented with one single escape mutation each; G145R, T126S, or PMID: 25737728
2014
Hepatitis monthly
Discussion: The MHR region contains residues 99-169 of HBsAg and T/I126S, Q129H, G130N, S143L, D144A, G145A, and G145R were among the commonly reported mutations.
Occult hepatitis B virus infection among blood donors in Colombia.
Discussion: Thirteen MHR mutations (G119R, P120T, C124R, C124Y, I126S, Q129R, S136P, C139R, T140I, K141E, D144A, G145A, and G145R) were detected and functionally characterized in vitro and in vivo.
HBV mutation literature information.
PMID: 
2015
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