Conclusion: Drug-resistant YMDD mutations caused a significant reduction in the antigenicity of immune-escaped HBsAg, particularly for the most common mutant sG145K.
Abstract: However, HBsAg mutation T123A was under quantified by the Architect, whereas HBsAg mutations P142L, P142S and G145K yielded lower results in the Elecsys system.
[Analysis of clinical characteristics and S gene mutation of hepatitis B virus (HBV) in patients with hepatitis B surface antigen RIA negative and HBV DNA positive].
PMID: 19571620
2009
The Korean journal of laboratory medicine
Abstract: G145R mutation was found in 8 patients and G145K, D144G, and D144A were also frequently found.
Hepatitis B virus with antigenically altered hepatitis B surface antigen is selected by high-dose hepatitis B immune globulin after liver transplantation.
Abstract: In addition to already-known variants sG145R/K/E, we could demonstrate that newly described variants sX144G and sG145A were antigenically altered and showed impaired recognition by polyclonal HBIG in vitro.
Emergence of hepatitis B virus S gene mutant in a liver transplant recipient.
Abstract: A double mutation generating an amino acid change (glycine to lysine) at residue 145, able to impair recognition by monoclonal antibodies, was observed in the post-transplant serum from one patient.
HBV mutation literature information.
PMID: 
2013
Virology journal
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