HBV mutation literature information.


  Detection of a hepatitis B surface antigen variant emerging in a patient with chronic lymphocytic leukaemia treated with fludarabine.
 PMID: 16789016       2006       Journal of medical virology
Abstract: Amino-acid sequence comparisons over the alpha determinant region revealed the following substitutions: C124N, G130R, and N146S.


  Prevalence of naturally occurring surface gene variants of hepatitis B virus in nonimmunized surface antigen-negative Chinese carriers.
 PMID: 11679975       2001       Hepatology (Baltimore, Md.)
1Abstract: These changes involved 11 positions inside and 5 outside of the historical first and second loops of the ""a"" determinant, and included the following: Q101K, T115A, K122N, T123A, T126N, Q129N, G130R, T131I, M133T, F134L, C138Y, K141E, P142S, G145R, N146S, and C147F/R."



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