Abstract: Mutated nucleotides of the Enh1/
X-promoter, especially
G1053A and
G1229A mutations in the HBV subgenotype C2 of patients with
cirrhosis, can be risk factors for hepatocarcinogenesis, and this might be due to an increase in the
HBx levels through the transactivation of the Enh1/
X-promoter.
Abstract: The sites that showed higher mutation rates in the
HCC group were
G1053A and
G1229A, which were found to be independent risk factors through multiple logistic analysis (P < 0.05).
HBV mutation literature information.
PMID: 
2010
Cancer science
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