Abstract: I127T,
V131I, and
F132Y/I/R mutations showed a significant increasing trend associated with the disease progression to
HCC.
Result: F132Y/I/R was present in 39.3% of
HCC patients, while it showed low prevalence in
LC (3.85%), AC (4%), and IC groups (4.49%).
Discussion: Further, it was observed that
H94Y and
F132Y/I/R mutations were present with high frequency only in the
HCC group, suggesting that these mutations were associated with an increased risk of
HCC
HBV mutation literature information.
PMID: 
2017
Oncotarget
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