Precore/core mutations of hepatitis B virus genotype D arising in different states of infection.
PMID: 35415256
2022
Clinical and experimental hepatology
Table: E77D
The Correlation Between Hepatitis B Virus Precore/Core Mutations and the Progression of Severe Liver Disease.
PMID: 30406036
2018
Frontiers in cellular and infection microbiology
Result: Considering the core mutation E77D/Q, D is absent in AC group but detectable at low frequency in the LC+HCC group.
Result: The amino acids at the four positions in the core protein that were significantly associated with disease progression (E64D, E77D/Q, A80I/T/V, and L116I) were found to be more variable in the LC+HCC group than in the AC group.
Table: E77D
Naturally occurring core immune-escape and carboxy-terminal mutations runcations in patients with e antigen negative chronic hepatitis B.
Abstract: Three core immune escape mutations were significantly higher in patients with coexisting precore stop codon compared with patients without precore stop codon mutation, cT12S (43 vs. 8%, p < 0.001), cS21T (16 vs. 3.4%, p < 0.026), and cE77D (30 vs. 4.5%, p < 0.002).
HBV mutation literature information.
PMID: 
2022
Clinical and experimental hepatology
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