rt269I Type of Hepatitis B Virus (HBV) Polymerase versus rt269L Is More Prone to Mutations within HBV Genome in Chronic Patients Infected with Genotype C2: Evidence from Analysis of Full HBV Genotype C2 Genome.
Result: C-Q182K/* (C2444A/T or A2445G mutation), of which the frequency tended to be higher in rt269I strains than in rt269L strains (q = 0.068), has been reported to be significantly related to HCC in Korean chronic patients infected with genotype C2.
Result: We found a total of three types of signature NS mutations in the preC/C region (one in the preC region: preC-W28Stop, two in the C region: C-I97F/L ( PMID: 22014121
2011
BMC cancer
HBV mutation literature information.
PMID: 
2021
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