literature

HBV mutation literature information.

Qidong hepatitis B virus infection cohort: a 25-year prospective study in high risk area of primary liver cancer.

PMID: 29479565 2018 Hepatoma research

Introduction: These mutations include A2159G, A2189C and G2203W at C gene, Introduction: While A1762T/G1764A, C1653T, A799G, A987G, T1055A, pre-S deletion could be detected in the plasma long before PLC diagnosis, T1753C, C1766T and T1768A mutations appeared only one or two years before PLC diagnosis.,,These observations provide valuable information for HCC prediction and screening when using HBV mutations as the marker.

Mutations in hepatitis B virus polymerase are associated with the postoperative survival of hepatocellular carcinoma patients.

PMID: 29287068 2017 PloS one

Introduction: A previous study indicated that the A799G, A987G, and T1055A mutations in the RT domain are predictive markers of HCC occurrence.

Novel natural mutations in the hepatitis B virus reverse transcriptase domain associated with hepatocellular carcinoma.

PMID: 24788140 2014 PloS one

Result: The crude ORs for A799G, A987G and T1055A were 3.37 (95% CI: 1.17-9.67), 6.08 (95%CI: 1.31-28.19) and 4.45 (95% CI: 1.72-11.54), respectively.

Discussion: Unlike the mutations A799G and T1055A, A987G does not cause an amino acid change in HBV <

Discussion: We found that the mutations A799G, A987G, and T1055A were detectable in >75% patients (3 of 4 patients for A799G, 2 of 2 patients for A987G, and 4 of 5 patients for T1055A) 4-5 years before the clinical diagnosis of HCC (Table S3 in File S1).

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