Potential Susceptibility Mutations in C Gene for Hepatitis B-Related Hepatocellular Carcinoma Identified by a Two-Stage Study in Qidong, China.
PMID: 27727182
2016
International journal of molecular sciences
Conclusion: Then, an independent case-control study revealed that the A2159G and A2189Y mutations were independent risk factors for HCC in chronic HBV-infected subjects in Qidong.
Discussion: Multivariate analysis indicated that pre-S deletion, A1762T/ Discussion: The key finding of this study was that the number and pattern of multiple mutations in the C gene (A2159G, A2189Y, G2203W, and C2288R mutations) showed the additive combined effects that related to HCC progression.
HBV mutation literature information.
PMID: 
2016
International journal of molecular sciences
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