Precore/core mutations of hepatitis B virus genotype D arising in different states of infection.
PMID: 35415256
2022
Clinical and experimental hepatology
Introduction: Additionally, they reported that A2051C increased the viral replication in vivo and in vitro.
Introduction: showed that the core mutations such as T1938C (V13A) and A2051C (N51H) were correlated with HBV-related HCC and played a role in progression of liver disease in an Alaskan native population with HBV genotype F1b.
An Association Between Core Mutations in Hepatitis B Virus Genotype F1b and Hepatocellular Carcinoma in Alaskan Native People.
Abstract: Clones containing the A2051C mutation replicated more efficiently than the wild type in association with enhanced stability of core protein dimerization.
Abstract: In the HCC patients, T1938C and A2051C mutations in the core region had accumulated significantly with A1762T/G1764A mutations in the basal core promoter (BCP) region and G1896A mutation in the precore (PC) region.
HBV mutation literature information.
PMID: 
2022
Clinical and experimental hepatology
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