Result: Of those 19 hotspot mutations,
C1653T,
T1674C/G,
A1703G,
G1719T,
T1727A/G,
T1753C,
A1762T,
G1764A,
G1799C,
G1899A,
G1915A/C, and
C1969T were significantly associated with an increased risk of
HCC, whereas
C1673T,
A1726C,
C1730G, and
A1752G were significantly associated with a reduced risk of
PMID: 26568165
2015
Scientific reports