literature

HBV mutation literature information.

Mutations in the HBV PreS/S gene related to hepatocellular carcinoma in Vietnamese chronic HBV-infected patients.

PMID: 35390033 2022 PloS one

Table: A159V

Investigation of immune escape-associated mutations of hepatitis B virus in patients harboring hepatitis B virus drug-resistance mutations.

PMID: 32994690 2020 World journal of gastroenterology

Result: The sA159V-positive patients had higher rates of coexisting drug-resistance mutations than the sA159V-negative patients.

Result: Three

Result: Three sA159V-containing resistant mutants had significantly higher replication capacities than their sA159V-lacking counterparts (M2 vs M3, M4 vs M5, M6 vs M7, all P < 0.05) (Figure 4).

Molecular and serological characterization of occult hepatitis B among blood donors in Maputo, Mozambique.

PMID: 32997000 2020 Memorias do Instituto Oswaldo Cruz

Table: A159V

Nearly half of Ultrio plus NAT non-discriminated reactive blood donors were identified as occult HBV infection in South China.

PMID: 31269905 2019 BMC infectious diseases

Table: A159V/G

Serological Patterns and Molecular Characterization of Occult Hepatitis B Virus Infection among Blood Donors.

PMID: 27882070 2016 Hepatitis monthly

Abstract: Mutations in the S region of HBV DNA included S114T, G119R, P120S, T125M, C139Y, T140I, C147W, T148A, A159V/G, E164D, V168A, and R169C.

Result: Variants were found in 30.4% (21/69) of cases with OBI and included S114T, G119R, P120S, T125M, C139Y, T140I,

Hepatitis B surface antigen variants in voluntary blood donors in Nanjing, China.

PMID: 22500577 2012 Virology journal

Result: D99N, Q101R/H, L109I, I110N, T115S, S117T, P120S, K122R, S126T/A, P127H, A128V, Q129R/H/L, G130E, T131N/A, M133T/L/S, F134R/I/L, T143M, A159V, F161Y, W163G, E164G, V168A

"Identification of hepatitis B surface antigen variants with alterations outside the ""a"" determinant in immunized Singapore infants."

PMID: 9841851 1999 The Journal of infectious diseases

1Abstract: Decreased binding to ""a"" determinant-specific monoclonal antibody was observed for variants Pro120 to Ser120, Ala159 to Val159, and Phe183 to Cys183."

Abstract: These include Asn116 to Thr116, Val118 to Ala118, Pro120 to Ser120, Ala159 to Val159, Phe183 to Cys183, and Val184 to Ala184.

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