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 EBV mutation literature information.


  Conserved mutation of Epstein-Barr virus-encoded BamHI-A Rightward Frame-1 (BARF1) gene in Indonesian nasopharyngeal carcinoma.
 PMID: 20849661       2010       Infectious agents and cancer
Abstract: At the protein level these mutations resulted in 3 main substitutions (V29A, W72G, H130R), which are not considered to cause gross tertiary structure alterations in the hexameric BARF1 protein.
Result: At the protein level most NPC (78.6%) demonstrated 2 amino acid substitutions at position V29A (valine to alanine) and H130R (histidine to arginine), except 1 sample (NPC-13) which displayed a unique conversion in the position of W72G and H130R.
Result: Some isolates (14.3%) showed rare mutations at position W72G (tryptophan to glycine).



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