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 EBV mutation literature information.


  Sequence variations of Epstein-Barr virus-encoded BARF1 gene in nasopharyngeal carcinomas and healthy donors from southern and northern China.
 PMID: 29797589       2018       Journal of medical virology
Abstract: For Chinese isolates, the B95-8 type was dominant in both southern and northern China, but the isolates from southern China showed a higher frequency of the B95-8t165545c subtype than the isolates from northern China (76.0%, 38/50 NPC cases and 50.7%, 37/73 healthy donors vs 26.4%, 24/91 NPC cases and 7.6%, 6/79 healthy donors, P < .0001).
Abstract: Furthermore, the B95-8t165545c subtype was more frequent in NPC cases than healthy donors in both southern China (P = .005) and northern China (P = .001).
Abstract: The B95-8t165545c subtype was only identified in Asia and demonstrated high frequency (81.2%, 26/32) in genomes from NPC case


  Conserved mutation of Epstein-Barr virus-encoded BamHI-A Rightward Frame-1 (BARF1) gene in Indonesian nasopharyngeal carcinoma.
 PMID: 20849661       2010       Infectious agents and cancer
Result: The C666-1 cell line showed 1 silent mutation at position of 165545 (T to C).
Discussion: reported variants of BARF1 gene on EBV cell lines from EBV-associated T/NK-cell lymphoma showing change of G to A at the position of 165554, change of T to C at 165589, and change of T to C at 165545.



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