Abstract: Variation analysis in
EBNA-2 functional domains: the TAD residue (
I438L) and the NLS residues (
E476G,
P484H and
I486T) were only detected in
NPC samples which located in the carboxyl terminus of
EBNA-2 gene.
Result: Interestingly, the four silent mutations and five non-silent mutations (
R413G,
I438L,
E476G,
P484H and
I486T) in this subtype were only detected in 12
NPC samples.
Result: Interestingly, the mutations in TAD residue (
I438L
EBV mutation literature information.
PMID: 
2012
Virology journal
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