Result: Polymorphisms I124V/I152L and F144I/D150A/L151I are not associated with HIV-HL.
Discussion: Polymorphisms Discussion: Taken together, our results showed that enhanced NF-kappaB activation resulted from single amino acid changes in the transmembrane segments 4 and 5 of the protein: F106Y, I124V and F144I.
Discussion: We observed that I124V/I152L and F144I/D150A/L151I, combined, were found in virus from more than 50% of the participants from each group.