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 EBV mutation literature information.


  Sequence analysis of Epstein-Barr virus EBNA-2 gene coding amino acid 148-487 in nasopharyngeal and gastric carcinomas.
 PMID: 22348267       2012       Virology journal
Abstract: Three variations (g48991t, c48998a, t49613a) were detected in all of the samples (113/113, 100%).
Result: Among the 20 loci with nucleotide changes, three nucleotide mutations (g48991t, c48998a and t49613a) were detected in all the EBVaGC, NPC and TW samples (113/113, 100%) (Figure 1).
Discussion: Of the three common mutations, amino acid mutation R163M and silent mutation c48998a were previously identified in 13 Korean isolates, 18 of 33 oral squamous cell carcinoma cases in Okinawa, Japan and 6


  Differences in EBNA2 and LMP-1 carboxy terminal region sequences of Epstein-Barr virus type A between the tumors in a multiple cancer patient.
 PMID: 11432667       2001       Pathology, research and practice
Abstract: The mutations at 48991 (G-->T) and 48998 (C-->A) were demonstrated in the lymphoma.



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