In-vivo analysis of hpv e7 protein association with prb, p107 and p130.
PMID: 21556519
1995
International journal of oncology
Abstract: However, association with p107 and p130 by the HPV 6 E7 protein was also increased by mutation of the arginine at position 4 with an aspartate.
Abstract: Substitution of the glycine at position 22 with an aspartate was the only mutation capable of increasing the ability of HPV 6 E7 protein to bind pRb.
Vacuolar H(+)-ATPase mutants transform cells and define a binding site for the papillomavirus E5 oncoprotein.
PMID: 7896830
1995
The Journal of biological chemistry
Abstract: More specifically, conversion of glutamic acid 143 to arginine within TM4 severely reduced 16K/E5 binding, suggesting that charged interactions facilitated efficient binding.
Abstract: This hypothesis was confirmed by demonstrating that binding to the defective 16K arginine mutant could be restored by complementary charge mutations in E5; conversion of E5 glutamine 17 to glutamic acid or aspartic acid enhanced interactions with the 16K arginine mutant.
Geographical dependence of sequence variation in the E7 gene of human papillomavirus type 16.
PMID: 1321216
1992
The Journal of general virology
Abstract: One tumour harbours HPV-16 DNA with a mutation (C to T) at nucleotide 790 changing the E7 amino acid sequence (arginine to cysteine) at position 76.
Mutational analysis of human papillomavirus type 16 E7 functions.
HPV mutation literature information.
PMID: 
1995
International journal of oncology
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