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HBV Target gene Detail Information

> UNKL Gene Search Result


Gene Information
Gene Name UNKL
Gene ID 64718
Gene Full Name unkempt family like zinc finger
Gene Alias ZC3H5L; C16orf28; ZC3HDC5L
Transcripts ENSG00000059145
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q9H9P5
HGNC ID HGNC:14184
VEGA ID OTTHUMG00000128553
OMIM ID 617463
String ID 9606.ENSP00000301712
PharmGKB ID PA37855
Target gene [UNKL] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000129 chr16 3189 1934 880 6003 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of UNKL expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
UNKL expression: Low -> High
Lollipop of UNKL expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of UNKL expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of UNKL expression and immune infiltrating cell level correlation result in HBV+ samples
UNKL expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).